David Bioinformatics Resources ((hot)) -

The "Elevator Pitch" That Changed Genomics

In the early 2000s, a biologist named Dr. Da Wei Huang had a frustrating problem. He had just run a microarray experiment and had a list of 500 genes that were "differentially expressed." He knew the names of these genes—BRCA1, TP53, AKT1—but he had no idea what they meant together.

Pathway Mapping: Visualizes user genes on standard biochemical maps like KEGG and BioCarta. david bioinformatics resources

Ortholog Tool: Allows users to convert gene lists between species (e.g., mouse to human) to leverage better-annotated model organisms for analysis. The "Elevator Pitch" That Changed Genomics In the

• Functional Annotation Chart — enrichment results with enrichment scores, p-values, multiple testing corrections, gene counts per term.
• Functional Annotation Clustering — groups related annotation terms into clusters with enrichment scores for higher-level interpretation.
• Visualization Tools — heat maps, gene-term annotation charts, bubble charts (term enrichment vs. gene count), and cluster visualizations.
• Gene ID Conversion Tool — maps among common ID types (Entrez, Ensembl, UniProt, gene symbols).
• Gene Functional Classification — groups genes by shared annotation profiles.
• Functional Annotation Table — per-gene annotations across many categories (GO, pathways, domains, disease associations).

David Bioinformatics Resources remains a cornerstone for bench scientists and computational biologists alike—bridging the gap between gene lists and biological discovery. Official Gene Symbols (e.g.

• Official Gene Symbols (e.g., TP53, EGFR)
• Accession numbers (e.g., NM_005228)
• Affymetrix probeset IDs
• Ensembl IDs, UniProt IDs, RefSeq IDs.