The "Failed to launch downloader" error in Cisco AnyConnect (now Cisco Secure Client) version 4.10 typically occurs when the ISE Posture module fails to initiate an update or check compliance
If the issue persists, your environment may be impacted by a documented Cisco bug: CSCvz27629 : Specifically affects AnyConnect v4.10 MR1 failed to launch downloader cisco anyconnect 410 top
Maya’s fingers trembled as she typed back: "AnyConnect error 410 TOP. I’m trying everything." The "Failed to launch downloader" error in Cisco